Hershey+and+Chase

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Martha Chase lived from 1927- August 8, 2003. She was an American geneticist who obtained her bachelor's degree from the college of Wooster in 1950 and a dectoral degree from the University of Southern California in 1964. She worked as a labratory assistant. =====

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Alfred Hershey was an American who lived from December 4, 1908- May 22, 1997. He received his Bachelor of Science at Michigan State University in 1930 and his Ph.D. in bacteriology in 1934, then later worked at the Department of Bacteriology at Washington University in St. Louis.  After experimentation, Hershey and Chase concluded that phage DNA (DNA in a bacteria virus) alone carries the instructions needed to replicate phages inside the bacteria so DNA is a genetic material. =====

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 __DISCOVERY:__    In 1952 they wanted to know which substance, the DNA or the protein shell (called a capsid) is the genetic material that directs the attack of bacterial viruses. They performed side-by-side experiments with separate bacteriophage (virus) cultures in which either the protein capsule was labeled with radioactive sulfur or the DNA core was labeled with radioactive phosphorus:   =====

Their experiment resulted in sulfur being found predominatly in the supernatant, and phosphorus found predominatly in the cell fraction, from which a new generation of infective phage can be isolated. They concluded that the active component of the bacteriophage that transmits the infective characteristic is the DNA. There is a clear correlation between DNA and genetic information.   [|http://www.accessexcellence.org/RC/VL/GG/hershey.html    __ BIBLIOGRAPHY :__ >
 * "The Hershey-Chase Experiment." __Access Excellence Resource Center__. 1994. 9 Apr. 2008 <[|http://www.accessexcellence.org/RC/AB/BC/Experiments_that_Inspire.html >.   
 * <span style="FONT-FAMILY: Georgia, serif"><span style="FONT-FAMILY: Georgia, serif">[|http://biology.clc.uc.edu/courses/bio104/dna.htm  </span]>
 * "Definition of Hershey-Chase Experiment." __MedicineNet.Com__. 11 Nov. 2004. 10 Apr. 2008 http://www.medterms.com/script/main/art.asp?articlekey=39044.